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Search Results for " non–small-cell lung cancer "

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カタログ番号	製品名	別名	ターゲット
T9929	Ramucirumab		VEGFR
	Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.		VEGFR
T10777	CG347B		HDAC
	CG347B is a selective inhibitor of HDAC6.		HDAC
T21588	Olomoucine		ERK , CDK
	Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an...		ERK , CDK
T2325	Neratinib	HKI-272	EGFR , HER
	Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.		EGFR , HER
T9865	Almonertinib mesylate		EGFR
	Almonertinib mesylate is an irreversible inhibitor of EGFR tyrosine kinase with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate can be used in the non-small cell lung cancer st...		EGFR
T8756	KRAS inhibitor-9	DUN09716	Apoptosis , Ras
	KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ...		Apoptosis , Ras
T60076	Oritinib	SH-1028	EGFR
	Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can ...		EGFR
T5462	Almonertinib	HS-10296	EGFR
	Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.		EGFR
T5675	Almonertinib hydrochloride	HS-10296 hydrochloride	EGFR
	Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.		EGFR
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T0373	Erlotinib	OSI-744,NSC 718781,CP358774,R1415	EGFR , Autophagy
	Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.		EGFR , Autophagy
T1758	ABT-751	E7010	Microtubule Associated , Autophagy
	ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.		Microtubule Associated , Autophagy
T15390	Glufosfamide	D 19575,Glucosylifosfamide mustard	Others
	Glufosfamide is a novel oxazolophosphamide compound with anticancer activity for the study of advanced non-small cell lung cancer.		Others
T36404L	PRLX-93936 HCL	PRLX-93936 hcl(903499-49-0 Free base)	Ferroptosis , Reactive Oxygen Species
	PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.		Ferroptosis , Reactive Oxygen Species
T30087	Antroquinonol		Reactive Oxygen Species , Nrf2
	Antroquinonol is a ubiquinone derivative from Antrodia camphorata with anti-inflammatory and anticancer activities.Antroquinonol reduces oxidative stress and inhibits inflammation and sclerosis in mice with focal segment...		Reactive Oxygen Species , Nrf2
T39275	Befotertinib	D-0316,Befotertinib	EGFR
	Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer.		EGFR
T0373L	Erlotinib hydrochloride	OSI-744,NSC 718781,Erlotinib HCl,CP-358774	EGFR , Autophagy
	Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.		EGFR , Autophagy
T67934	MRT-2359		Others
	MRT-2359 is a potent and orally available GSPT1 reducer with antitumour activity.MRT-2359 inhibits the growth of drug-resistant non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells.MRT-2359 exhibits...		Others
T9673	RET-IN-3		c-RET
	RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.		c-RET
T72043	SCFSkp2-IN-2		Apoptosis , E1/E2/E3 Enzyme
	SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM. It demonstrates antitumor activities by inducing apoptosis in non-small cell lung cancer (NSCLC) cells.		Apoptosis , E1/E2/E3 Enzyme
T6084	Rabusertib	LY2603618,IC-83	Chk , PDK , Autophagy
	Rabusertib (IC-83) is an inhibitor of the cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiating activity. Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cance...		Chk , PDK , Autophagy
T76792	Sibrotuzumab	BIBH 1,Anti-Human FAP Recombinant Antibody	Others
	Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targeting Fibroblast Activating Protein (FAP).Sibrotuzumab is used in the study of colorectal cancer and non-small cell lung cancer.		Others
T13564L2	AZ7550 trimesylate salt	AZ7550 Mesylate,AZ7550 trimesylate salt (1421373-99-0 free base)	MLK
	AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 trimesylate salt inhibits IGF1R activity and can be used in the study of non-small cell lung cancer.		MLK
T9901A-002	Enoblituzumab	MGA271,TJ-271	Others
	Enoblituzumab is a humanized IgG1 κmab monoclonal antibody that recognizes human B7-H3 protein and can be used to study solid tumors such as non-small cell lung cancer (NSCLC).		Others
T35901	EGFR-IN-99	JBJ-03-142-02	EGFR , HER
	EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor with antiproliferative activity for the study of non-small cell lung cancer (NSCLC).		EGFR , HER
T40292	Opnurasib	NVP-JDQ443,JDQ-443,Opnurasib	Ras
	Opnurasib (JDQ-443) is an orally available and selective and potent covalent KRAS G12C inhibitor with antitumor activity for the study of advanced non-small cell lung cancer.		Ras
T61016	EMI1		EGFR
	EMI1 can be used in the mutant EGFR-associated, drug-resistant non-small-cell lung cancer(NSCLC) research. EMI1 is an inhibitor of EGFR L858R/T790M/C797S and EGFR ex19del/T790M/C797S [1].		EGFR
T35391	Vibostolimab (anti-TIGIT)	Vibostolimab (anti-TIGIT)	Others
	Vibostolimab is a monoclonal antibody against T cell immune proteins and the ITIM domain.Vibostolimab has shown anti-tumor activity in in vitro trials and can be used to study non-small cell lung cancer (NSCLC) and melan...		Others
T9754	BLU-945	BLU945,BLU 945	EGFR
	BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, effective against EGFR with L858R and/or exon 19 deletion mutations, T790M, and C797...		EGFR
T9460	IMDK		PI3K
	iMDK quarterhydrate is a potent PI3K inhibitor that inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate synergistically inhibits non-small cell lung cancer (NSCLC) with MEK inhibitors withou...		PI3K
T76796	Patritumab	U3-1287,AMG-888	ERK , EGFR , Akt , HER
	Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-sm...		ERK , EGFR , Akt , HER
T60039	KSQ-4279	USP1-IN-1	PARP , DUB
	KSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP.KSQ-4279 has anticancer activity and is used in the study of non-small cell lung cancer, osteosarcoma, ovarian, breast, glioblastoma, bladder, uterine and pancreatic ...		PARP , DUB
T36316	MTOR inhibitor-8	mTOR-IN-8	mTOR , Autophagy
	mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activity. mTOR inhibitor-8 inhibits the growth of A549 cells, which can be used to study non-small cell lung cancer.		mTOR , Autophagy
T35394	Sintilimab (anti-PD-1)	IBI308,Sintilimab (anti-PD-1)	PD-1/PD-L1
	Sintilimab (IBI308) is a humanized IgG4 monoclonal antibody with significant anti-tumor activity that restores endogenous anti-tumor T-cell responses by binding to PD-1 and thereby blocking the interaction of PD-1 with i...		PD-1/PD-L1
T35392	Tiragolumab	RO 7092284,RG6058-10,MTIG-7192A,RG6058-11,RG-6058	Others
	Tiragolumab(MTIG-7192A) is a monoclonal antibody that targets T-cell immunoglobulin and the ITIM structural domain (TIGIT).Tiragolumab is often used in combination with the PD-L1 inhibitor, Atezolizumab, for the treatmen...		Others
T14997	Conteltinib	SY-707,CT-707	FAK , PYK2 , ALK
	Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carci...		FAK , PYK2 , ALK
T72784	OTUB1/USP8-IN-1		DUB
	OTUB1/USP8-IN-1 is a potent OTUB1/USP8 inhibitor with potential anticancer activity, with IC50 values of 0.17 and 0.28 nM for OTUB1 and USP8, respectively.OTUB1/USP8-IN-1 can be used in the study of non-small-cell lung c...		DUB
T72953	Zidesamtinib	NVL-520	ROS Kinase
	Zidesamtinib (NVL-520) is an orally active, selective, potent, and blood-brain-barrier-crossing inhibitor of ROS1 fusion and resistance mutations, inhibits ROS1 and ROS1 G2032R, and can be used in the study of non-small-...		ROS Kinase
T2490	Osimertinib	AZD-9291,Mereletinib	EGFR
	Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activi...		EGFR
T63343	ULK1-IN-2		Apoptosis , Autophagy
	ULK1-IN-2 is a potent ULK1 inhibitor with potential anticancer activity, inducing apoptosis while blocking autophagy.ULK1-IN-2 has high cytotoxicity against cancer cells, with an IC50 value of 1.94 μM against A549 cells....		Apoptosis , Autophagy
T22443	Triglycidyl isocyanurate	Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI	Apoptosis
	Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk...		Apoptosis
T77401	Bavituximab	Anti-PS MAb 3G4	Others
	Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a monoclonal antibody against phosphatidylserine (PS) with vascular targeting and immunomodulatory properties. It can reactivate anti-tumor immunity to ...		Others
T61575	USP15-IN-1		DUB
	USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity against non-small cell lung cancer and leukemia cells. USP15 is an interacting protein of cGAS, and USP15 can pr...		DUB
T11067	VX-984	M9831	DNA-PK
	VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commo...		DNA-PK
T0189L	Pemetrexed disodium	LY-231514,LY231514 disodium,Pemetrexed	Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
	Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b...
T11126	Durvalumab	MEDI 4736	PD-1/PD-L1
	Durvalumab (MEDI 4736) is a humanized monoclonal antibody targeting PD-L1. It can block the interaction of PD-L1 with PD-1 and CD80, with IC50 values of 0.1 and 0.04 nM, respectively. Durvalumab is often used in combinat...		PD-1/PD-L1
T9972	Divarasib	GDC-6036	Ras
	Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of < 0.01 μM. Divarasib irreversibly locks KRAS G12C oncoprotein in an inactive state and inhibi...		Ras
T69529	BI-0474		Ras
	BI-0474 is a potent KRASG12C inhibitor that inhibits GDP-KRAS::SOS1 protein-protein interactions with an IC50 value of 7.0 nM.BI-0474 exhibits significant antiproliferative activity against NCI-H358 cells harboring the G...		Ras
T76873	Nidanilimab	CAN04	IL Receptor
	Nidanilimab (CAN04) is a fully humanized IL1RAP monoclonal antibody with a Kd value of 1.10 pM. Nidanilimab has antitumor activity, cutting off the IL1α and IL1β signaling pathways and inducing the immune system to destr...		IL Receptor
T64529	MDL-800	MDL 800,MDL800	Sirtuin
	MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.		Sirtuin

Compounds

Almonertinib mesylate

Target: Apoptosis, Ras

Almonertinib hydrochloride

T5675

Synonym: HS-10296 hydrochloride

Target: EGFR

CAY10404

T8656

Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Target: Apoptosis, Akt, COX

Erlotinib

T0373

Synonym: OSI-744,NSC 718781,CP358774,R1415

Target: EGFR, Autophagy

ABT-751

T1758

Synonym: E7010

Target: Microtubule Associated, Autophagy

Glufosfamide

T15390

Synonym: D 19575,Glucosylifosfamide mustard

Target: Others

PRLX-93936 HCL

T36404L

Synonym: PRLX-93936 hcl(903499-49-0 Free base)

Target: Ferroptosis, Reactive Oxygen Species

Antroquinonol

T30087

Synonym:

Target: Reactive Oxygen Species, Nrf2

Befotertinib

T39275

Synonym: D-0316,Befotertinib

Target: EGFR

Erlotinib hydrochloride

T0373L

Synonym: OSI-744,NSC 718781,Erlotinib HCl,CP-358774

Target: EGFR, Autophagy

Target: Apoptosis, E1/E2/E3 Enzyme

Rabusertib

T6084

Synonym: LY2603618,IC-83

Target: Chk, PDK, Autophagy

Sibrotuzumab

T76792

Synonym: BIBH 1,Anti-Human FAP Recombinant Antibody

Target: Others

AZ7550 trimesylate salt

T13564L2

Synonym: AZ7550 Mesylate,AZ7550 trimesylate salt (1421373-99-0 free base)

Target: MLK

Enoblituzumab

T9901A-002

Synonym: MGA271,TJ-271

Target: Others

EGFR-IN-99

T35901

Synonym: JBJ-03-142-02

Target: EGFR, HER

Opnurasib

T40292

Synonym: NVP-JDQ443,JDQ-443,Opnurasib

Vibostolimab (anti-TIGIT)

T35391

Synonym: Vibostolimab (anti-TIGIT)

Target: Others

BLU-945

T9754

Synonym: BLU945,BLU 945

Synonym: U3-1287,AMG-888

Target: ERK, EGFR, Akt, HER

Target: mTOR, Autophagy

Sintilimab (anti-PD-1)

T35394

Synonym: IBI308,Sintilimab (anti-PD-1)

Target: PD-1/PD-L1

Tiragolumab

T35392

Synonym: RO 7092284,RG6058-10,MTIG-7192A,RG6058-11,RG-6058

Target: Others

Conteltinib

T14997

Synonym: SY-707,CT-707

Target: FAK, PYK2, ALK

Synonym: AZD-9291,Mereletinib

Target: Apoptosis, Autophagy

Triglycidyl isocyanurate

T22443

Synonym: Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI

Target: Apoptosis

Bavituximab

T77401

Synonym: Anti-PS MAb 3G4

Synonym: LY-231514,LY231514 disodium,Pemetrexed

Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy

Synonym: MDL 800,MDL800

Target: Sirtuin

カタログ番号	製品名	別名	ターゲット
T2870	Matrine	Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
	Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.		Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
T7849	Norspermine		Others
	Norspermine is a polyamine analogue ,used in the treatment of non-small cell lung carcinoma and breast cancer.		Others
T25192	Butyrolactone I	Olomoucin	CDK
	Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines.		CDK
TN1721	Gypenoside L		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
TN3972	Epimedokoreanin B		Apoptosis , Others , Antibacterial
	Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-...		Apoptosis , Others , Antibacterial
TN3355	Agatharesinol acetonide		Antifection
	Agatharesinol acetonide shows anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM).		Antifection
TN1872	Linderone		Others
	Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line.		Others
TN4355	Jolkinol A		Others
	Jolkinol A can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM.		Others
TN1642	Ferruginol		BCL , PARP , Caspase
	Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.		BCL , PARP , Caspase
TN6062	1,3,9-Trimethyluric acid
	1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the ran...
TN4166	Griffipavixanthone		ERK , Raf , ROS , MEK , Caspase
	Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS productio...		ERK , Raf , ROS , MEK , Caspase
TN5254	Wighteone	Erythrinin B,6-Isopentenylgenistein	Antifungal
	Wighteone (Erythrinin B) is a small molecule compound derived from Genista ephedroides with potential antifungal and anticancer activity against EGFR L858R/T790M mutant non-small cell lung cancer.		Antifungal
T11009	Destruxin B		Others
	Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Metarhizium isopliae. Destruxin B induces apoptosis of human non-small cell lung cancer cells through t...		Others
TN5440	Catechin-7-O-xyloside	Catechin 7-O-β-D-xylopyranoside	Others
	Catechin-7-O-xyloside(C7Ox) has anti-cancer activity, it induces apoptosis via endoplasmic reticulum stress and mitochondrial dysfunction in human non-small cell lung carcinoma H1299 cells.		Others
TN4774	Physalin A		ERK , BCL , p38 MAPK , NF-κB , Androgen Receptor , ROS , JAK , JNK , STAT , p53 , Autophagy
	Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and dow...
T81132	Soladulcoside A
	Soladulcoside A, a steroidal glycoside with antineoplastic properties, is derived from the entire Solanum nigrum plant. It demonstrates inhibitory effects on A549 cells, suggesting its applicability in researching non-sm...
T81201	Sartorypyrone B
	Sartorypyrone B, a 2β-acetoxyl analogue of chevalone C, is derived from the ethyl acetate extract of the culture of Neosartorya tsunodae (KUFC 9213), a fungus associated with marine sponges. This compound demonstrates po...

天然物製品

Matrine

T2870

Synonym: Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine

Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Epimedokoreanin B

TN3972

Synonym:

Target: Apoptosis, Others, Antibacterial

Agatharesinol acetonide

Target: BCL, PARP, Caspase

1,3,9-Trimethyluric acid

Target: ERK, Raf, ROS, MEK, Caspase

Wighteone

TN5254

Synonym: Erythrinin B,6-Isopentenylgenistein

Catechin-7-O-xyloside

TN5440

Synonym: Catechin 7-O-β-D-xylopyranoside

Target: ERK, BCL, p38 MAPK, NF-κB, Androgen Receptor, ROS, JAK, JNK, STAT, p53, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-03958	TGF alpha Protein, Human, Recombinant	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01008	VEGFD Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-01730	CD24 Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03016	CD24 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01298	CADM1 Protein, Human, Recombinant (His)	Human	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular...
TMPK-00906	PSCA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPK-00728	PSCA Protein, Human, Recombinant (hFc)	Human	HEK293
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPK-00340	ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00339	ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00341	ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-01034	SEMA4B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling p...
TMPY-01069	VEGFR3/FLT4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01937	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-06620	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-06249	CCK4/PTK7 Protein, Human, Recombinant (His)	Human	HEK293
	Protein tyrosine kinase 7 (PTK7) is a highly conserved but catalytically inactive receptor tyrosine kinase in the Wnt signaling pathway. PTK7 regulates various processes in embryonic development and tissue homeostasis. O...
TMPY-06250	CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Protein tyrosine kinase 7 (PTK7) is a highly conserved but catalytically inactive receptor tyrosine kinase in the Wnt signaling pathway. PTK7 regulates various processes in embryonic development and tissue homeostasis. O...
TMPK-01143	LRIG1 Protein, Human, Recombinant (His)	Human	HEK293
	The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, whic...
TMPK-00513	LRIG1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, whic...
TMPY-04375	Casein Kinase 1 alpha Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein k...
TMPY-03200	VEGFD Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-02589	VEGFD Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-03150	VEGFD Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-05298	CD24 Protein, Human, Recombinant (rFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02399	TRF1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPY-06940	CD24 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05299	CD24 Protein, Human, Recombinant (mFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03032	CD24 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02796	KIAA0101 Protein, Human, Recombinant (His)	Human	E. coli
	KIAA11, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor that interacts with proliferating cell nuclear antigen(PCNA). It was initially isolated in a yeast two-hybrid screen for PCNA bind...
TMPY-04417	DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)	Human	Baculovirus-Insect Cells
	Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK...
TMPY-03208	CD164 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a novel 80- to 90-kD mucin-like molecule expressed by human CD34+ hematopoietic progenitor cells. Isoform 1 and isoform 3 of C...
TMPY-02067	CD164 Protein, Human, Recombinant (His)	Human	HEK293
	Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a novel 80- to 90-kD mucin-like molecule expressed by human CD34+ hematopoietic progenitor cells. Isoform 1 and isoform 3 of C...
TMPY-00092	CD164 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a novel 80- to 90-kD mucin-like molecule expressed by human CD34+ hematopoietic progenitor cells. Isoform 1 and isoform 3 of C...
TMPJ-00281	CADM1 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C...
TMPY-03684	REG1A Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-03092	REG1A Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-01335	REG1A Protein, Human, Recombinant (His)	Human	HEK293
	Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-03639	REG1A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-05474	REG1A Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Regenerating (reg) gene encodes protein that has been involved in pancreatic lithogenesis and the regeneration of islet cells and therefore the abnormality of reg genes could be associated with fibrocalculous pancreatopa...
TMPY-04499	CADM1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular...

VEGFR3/FLT4 Protein, Human, Recombinant (His)

TMPY-00949

Species: Human

Expression System: HEK293

TGF alpha Protein, Human, Recombinant

TMPY-03958

Species: Human

Expression System: E. coli

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

TMPY-01936

Species: Mouse

Expression System: HEK293

VEGFD Protein, Human, Recombinant (His)

TMPY-01008

Species: Human

Expression System: HEK293

CD24 Protein, Human, Recombinant (hFc)

TMPY-01730

Species: Human

Expression System: HEK293

CD24 Protein, Mouse, Recombinant (hFc)

TMPY-03016

Species: Mouse

Expression System: HEK293

CADM1 Protein, Human, Recombinant (His)

TMPY-01298

Species: Human

Expression System: HEK293

PSCA Protein, Mouse, Recombinant (hFc)

TMPK-00906

Species: Mouse

Expression System: HEK293

PSCA Protein, Human, Recombinant (hFc)

TMPK-00728

Species: Human

Expression System: HEK293

ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00340

Species: Human

Expression System: HEK293

ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-00339

Species: Mouse

Expression System: HEK293

ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00341

Species: Human

Expression System: HEK293

SEMA4B Protein, Mouse, Recombinant (His)

TMPK-01034

Species: Mouse

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (hFc)

TMPY-01069

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)

TMPY-01937

Species: Mouse

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06620

Species: Human

Expression System: HEK293

CCK4/PTK7 Protein, Human, Recombinant (His)

TMPY-06249

Species: Human

Expression System: HEK293

CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-06250

Species: Cynomolgus,Rhesus

Expression System: HEK293

LRIG1 Protein, Human, Recombinant (His)

TMPK-01143

Species: Human

Expression System: HEK293

LRIG1 Protein, Cynomolgus, Recombinant (His)

TMPK-00513

Species: Cynomolgus

Expression System: HEK293

Casein Kinase 1 alpha Protein, Human, Recombinant (GST)

TMPY-04375

Species: Human

Expression System: Baculovirus-Insect Cells

VEGFD Protein, Rat, Recombinant (hFc)

TMPY-03200

Species: Rat

Expression System: HEK293

VEGFD Protein, Mouse, Recombinant (hFc)

TMPY-02589

Species: Mouse

Expression System: HEK293

VEGFD Protein, Mouse, Recombinant (His)

TMPY-03150

Species: Mouse

Expression System: HEK293

CD24 Protein, Human, Recombinant (rFc)

TMPY-05298

Species: Human

Expression System: HEK293

TRF1 Protein, Human, Recombinant (His)

TMPY-02399

Species: Human

Expression System: Baculovirus-Insect Cells

CD24 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-06940

Species: Human

Expression System: HEK293

CD24 Protein, Human, Recombinant (mFc)

TMPY-05299

Species: Human

Expression System: HEK293

CD24 Protein, Rat, Recombinant (hFc)

TMPY-03032

Species: Rat

Expression System: HEK293

KIAA0101 Protein, Human, Recombinant (His)

TMPY-02796

Species: Human

Expression System: E. coli

DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)

TMPY-04417

Species: Human

Expression System: Baculovirus-Insect Cells

CD164 Protein, Rat, Recombinant (hFc)

TMPY-03208

Species: Rat

Expression System: HEK293

CD164 Protein, Human, Recombinant (His)

TMPY-02067

Species: Human

Expression System: HEK293

CD164 Protein, Cynomolgus, Recombinant (hFc)

TMPY-00092

Species: Cynomolgus

Expression System: HEK293

CADM1 Protein, Mouse, Recombinant (hFc)

TMPJ-00281

Species: Mouse

Expression System: Human Cells

REG1A Protein, Cynomolgus, Recombinant (hFc)

TMPY-03684

Species: Cynomolgus

Expression System: HEK293

REG1A Protein, Rat, Recombinant (hFc)

TMPY-03092

Species: Rat

Expression System: HEK293

REG1A Protein, Human, Recombinant (His)

TMPY-01335

Species: Human

Expression System: HEK293

REG1A Protein, Cynomolgus, Recombinant (His)

TMPY-03639

Species: Cynomolgus

Expression System: HEK293

REG1A Protein, Human, Recombinant (His), Biotinylated

TMPY-05474

Species: Human

Expression System: HEK293

CADM1 Protein, Mouse, Recombinant (His)

TMPY-04499

Species: Mouse

Expression System: HEK293

カタログ番号	製品名
L2190	Anti-Lung Cancer Compound Library		1702 compounds
	A unique collection of 1702 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study；

ライブラリー

Anti-Lung Cancer Compound Library

L2190

Compounds: 1702